Clinical features of familial mediterranean fever: an italian overview
Familial Mediterranean Fever (FMF) is the most frequent periodic febrile syndrome among the autoinflammatory syndromes (AS), nowadays considered as innate immunity disorders, characterized by absence...
View ArticleGastrointestinal amyloidosis: a case of chronic diarrhoea
Amyloidosis is a rare disease caused by extracellular deposits of insoluble fibrillar proteins in various organs and tissues. There are different forms of amyloidosis distinguished by the type of...
View ArticleAtypical sarcoidosis: case reports and review of the literature
Sarcoidosis is a granulomatous disease of unknown origin, with pulmonary findings in more than 90% of patients. Extrapulmonary involvement is common and all organs can be involved (especially lymph...
View ArticleNew therapeutic approach in inflammatory bowel disease
In the last decade, biologic agents, in particular infliximab and adalimumab, have deeply changed the therapeutic armamentarium of inflammatory bowel disease (IBD). However, these drugs have a number...
View ArticleExtradigestive manifestations of IBD in pediatrics
Inflammatory bowel diseases (IBD) are often associated with extraintestinal manifestations (EIMs), which occur in approximately one third of patients. There is only few published data on the occurrence...
View ArticleDermatological signs during inflammatory bowel diseases
Crohn disease (CD) and Ulcerative Colitis (UC) are characterized by ulcerative lesions of the bowel. Some patients show similar lesions of the skin or oral and/or perianal mucosa. Sometimes these...
View ArticleOphthalmological aspects of IBD
Ocular manifestations occur in 4-12% of patients with IBD. Uveitis and iritis are more frequently associated with ulcerative colitis while episcleritis is more common in Crohn’s disease. Some ocular...
View ArticleImmunologic and genetic links between spondylarthropathies and inflammatory...
Background and Objective: Spondyloarthritis (SpA) is a well recognized extraintestinal manifestation of Inflammatory Bowel Diseases (IBDs), either Crohn’s Disease(CD) or Ulcerative Colitis (UC). A much...
View ArticleCyclosporine A: good response for patients affected by autoimmune disorders...
Introduction: In autoimmune disorders (ADs), if Hepatitis C Virus (HCV) is present, immunosuppressive treatment could increase virus replication. Cyclosporine A (CsA), in standard therapeutic doses,...
View ArticleMesenchymal stromal cells multipotency and plasticity: induction toward the...
Background: Human mesenchymal stromal cells (MSCs) can be isolated from a variety of adult and perinatal tissues and exert multipotency and self renewal properties which make them suitable for...
View ArticleIsolation and characterization of CD133+ cell population within human primary...
Background, “Cancer stem cells” (CSC) have been identified as a minority of cancer cells responsible for tumor initiation, maintenance and spreading. Although a universal marker for CSC has not yet...
View ArticleAtypical sarcoidosis: case reports and review of the literature
Sarcoidosis is a granulomatous disease of unknown origin, with pulmonary findings in more than 90% of patients. Extrapulmonary involvement is common and all organs can be involved (especially lymph...
View ArticleNew therapeutic approach in inflammatory bowel disease
In the last decade, biologic agents, in particular infliximab and adalimumab, have deeply changed the therapeutic armamentarium of inflammatory bowel disease (IBD). However, these drugs have a number...
View ArticleGastrointestinal amyloidosis: a case of chronic diarrhoea
Amyloidosis is a rare disease caused by extracellular deposits of insoluble fibrillar proteins in various organs and tissues. There are different forms of amyloidosis distinguished by the type of...
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